Adrian Mathews (503) 353-8968 
adrian@iwr.com

90 day 
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Trans Resveratrol is 1000 times 
More Powerful than all other Resveratrol. 
Patented proprietary from The Japanese Knot Weed best form of Resveratrol, 
400 mg per serving.
 


Japanese Knot Weed

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Have you heard about the amazing benefits of Resveratrol?  

RESVERATROL (Polygonum Cuspidatum)

Resveratrol is reported by the media with excited anticipation of its potential in the metabolic support of the immune system, anti-aging, sports performance, many health concerns, and life extension. Resveratrol, found in red grapes, fruits, berries and root extracts, was first isolated in 1940 as a constituent of Japanese Knotweed and the Hy Zhang Root Extract (Polygonum capsidatum). The bio-active chemical configuration is 3,4’,5-tri-hydroxy-trans-stilbene, a potent antioxidant. It is a powerful antioxidant that exists as two geometric isomers: cis-resveratrol and trans- resveratrol – the latter being the naturally occurring form. It is trans-resveratrol that is the nutritional supplement product of which all research, regarding the benefits of the compound, are conducted upon.

Featured on the Barbara Walters special “Live to 150,” Resveratrol has been in the news a great deal! Led by Dr. David Sinclair at Harvard University, research studies continue to find more interesting benefits from this compound, including potentially staggering health benefits and life extension activity. 

It is not surprising that Resveratrol is shaping up to be the greatest nutritional discovery of our lifetimes. The media has nick-named Resveratrol as the “fountain of youth”.

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Beginning November 1, 2006 nearly 500 newspapers reported on the resveratrol story and virtually every major TV news department followed. The news media heralded a study which showed that a high-dose, “red wine molecule”, maintained the quality of life of laboratory mice (balance and coordination) as they aged despite a high-fat diet the high-fat fed mice lived 31% longer when given resveratrol.

Next, the anti-nutritional supplement news media began swaying consumers towards wine (as a source of resveratrol) because, as some authorities claimed, there was an uncertainty over the sources and safety of resveratrol supplementation. Forget that the EPA deems resveratrol to be non-toxic. Forget that animal studies show the equivalent of 21,000 milligrams in humans would be non-toxic.

Forget that three human clinical trials using 500 milligrams of resveratrol have passed the safety arm of their study. Forget that the National Institute of Environmental Health Sciences has conducted a toxicity review of resveratrol, and no major side effects are noted. For the record, resveratrol is far safer than any alcoholic beverage and is said to be safer than aspirin. When an alternative to an alcoholic beverage was available, a fact which should have been heralded, the news media, in a phobic aversion to dietary supplements, advised the public to “get drunk” on wine. So 90 percent of the news reports said, until proven otherwise, wine was safer than pills. Conversely, reporters further explained it would take too much wine to produce the same health benefits as shown in the recent study and consumers would have to drink about a case of wine per day to achieve the health benefits.

In a widely publicized report, researchers at Harvard Medical School and BIOMOL Laboratories have demonstrated that resveratrol activates a “longevity gene” by activating a cell’s survival defense enzyme, which prolongs the time cells have to repair their broken DNA.

One of the known causes of aging and death is that older cells lose their ability to perfectly replicate DNA in every new cell. DNA “mistakes” accumulate and allow little pieces of DNA to become active and print themselves out, so to speak, creating a type of “DNA debris” that eventually stops a cell from functioning effectively. 

It is similar to printing out a report and having a couple of pages at the end not contain any relevant information-so you throw them away. 
The cell can’t throw away the extra “printed out” DNA; it accumulates and clogs up the cell. This build up of “debris” is connected to aging, and the death of individual cells. Resveratrol has been shown to reduces the frequency of “DNA debris” by 60% through the longevity gene that is stimulated.

Resveratrol’s ability to activate the gene has to do with its chemical structure, not its antioxidant potential. It works by increasing the rate of a reaction known as “deacetylation.” Acetylation reactions affect whether a gene is “off” or “on.” By controlling deacetylation and augmenting the longevity gene, resveratrol is able to confer some serious life extension and health benefits-at least in the laboratory organisms.

Resveratrol may provide joint support and support the body’s defense system. Studies have shown that it may delay age related deterioration and mimic the effect of calorie restriction; Activate intracellular pathways crucial for antioxidant defense, regulate the cell cycle, increase mitochondrial energy production, vascular tone, and abnormal cell suppression. It has been proposed that Resveratrol is one of the most important dietary constituents involved in blood vessel health, possibly helping protect the heart from age and stress; it also has the potential benefits of energy, increased endurance and agility; possibly contributing to overall health and wellness.*

SYNERGISTIC PROPRIETARY ACTIVATING BLEND

QUERCETIN (Sophora Flavescens)

A bioflavonoid that has strong antioxidant properties and additional health benefits; is reported to have the ability to stabilize cell membranes, which may prevent histamines from spilling out of mast cells into the bloodstream and surrounding tissues; thereby making the cells less likely to respond with exaggerated or abnormal reactions to substances. 

May soothe and comfort joints, help strengthen the immune system, and have gastro protecting properties. Reportedly blocks the flow of nutrients to diseased cells and may help fight viruses, 
and microbial invaders. 

It is said to improve lung function and may help the lungs deal with dust and particle pollution. 
Promote optimal heart, brain and blood vessel health; enhance general and fat metabolism. 
Known to help protect capillaries and prevent bruising. Help the body with collagen production and protect elasticity. *

BAICALEIN (Scutellaria Lateriflora)

A constituent of a Chinese herb that has been used for more than a thousand years in China and Japan. A flavonoid known for its calming effects may calm the nerves and stimulate the production of endorphins, possibly improving mood and enhancing awareness, while protecting red blood cells from free radical damage. 

May suppress joint discomfort, help with the alleviation of body discomfort and help the body fight viruses and bacteria. It may help regulate immune response in challenging conditions. 

May protect DNA from cell mutations and inhibit the proliferation of abnormal cells. 
May produce stress relieving and relaxing abilities which may promote more restful sleep.*

GRAPE SEED EXTRACT (Vitis Vinifera / Proanthenols)

Helps protect against the harmful effects of oxidative stress, may make the cells less likely to respond with exaggerated or abnormal reactions to substances and may aid the body in the fight against harmful bacteria. 

It may reduce the swelling process, comforting joints; promote cardio vascular protection, help improve circulation, aid in the resistance of bruising; enhance the immune system and help the body to recover more quickly from stress. 

Strengthen and protect living tissue, help reduce the rate of aging and wrinkling of the skin; help reduce mental aging and enhance energy. *

These statements have not been evaluated by the Food and Drug Administration. 
This product is not intended to diagnose, treat, cure, or prevent any disease. 
People with medical concerns should check with their physician before using this or any dietary supplement.

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Adrian Mathews (503) 353-8968 or adrian@iwr.com

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